El tumor puede ser papilar, polipoide, plano o ulcerado. Histological section of keratinising squamous carcinoma. Note keratin whorls and chords of tumour tissue invading the stroma. Histological section of non keratinising squamous carcinoma. There are some chords of tumour tissue invading the stroma which also contains inflammatory cells and discrete bizare tumour cells with abnormal nuclei and abundant cytoplasm.
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La Habana, Cuba. Objective: present a clinical case of primary intraosseous carcinoma arising from an odontogenic cyst in body regions to the left mandibular branch. Clinical case: a year-old male patient presented with "discomfort" in his mandible. Oral examination revealed cortical expansion at the level of Orthopantomography showed a radiolucent area with definite borders. Curettage and histological testing confirmed the preliminary diagnosis of residual cyst. Some four months later the patient presented again with very intense pain in the mandibular angle region with slight paresthesia of the left lower lip area associated on physical facial examination with lower and submandibular genian edema, and on oral examination with abnormal left mandibular bone mobility.
Orthopantomography revealed a radiolucent image of irregular, imprecise borders and pathological mandibular fracture. It was decided to immobilize and take a sample for biopsy, which reported moderately differentiated epidermoid carcinoma. Therefore, radical surgical treatment was performed with neck management plus postoperative radiotherapy and chemotherapy.
Conclusion: evolution of a residual cyst into a primary intraosseous carcinoma is an infrequent condition in the maxillofacial region. In the case herein presented diagnosis was made by exclusion.
The symptoms of intense pain and paresthesia were crucial to the preliminary diagnosis. Application of an oncological approach based on radical surgery with neck management and radio- and chemotherapy resulted in local-regional control. Keywords: maxillomandibular neoplasms; squamous cell carcinoma; osseous cysts; mandible.
El paciente cursa con 8 meses de posoperatorio sin presentar recurrencia tumoral. El autor no declara conflicto de intereses. Solid-type primary intraosseous squamous-cell carcinoma in the mandible: Report of a rare case. Hematol Oncol Stem Cell Ther. Primary intraosseous squamous cell carcinoma in odontogenic keratocyst: A rare entity. J Oral Maxillofac Pathol.
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A retrospective study of six patients with mandibular metastatic carcinoma. Metastatic clear cell variant of renal cell carcinoma of the mandible: Review and case report.
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De novo type 3 primary intraosseous carcinoma of the jaws. Massive mandibular destruction and alveolar nerve infiltration without lower lip paresthesia in primary intraosseous carcinoma: report of two cases and critical appraisal of diagnostic criteria. Quintessence Int. J Oral Maxillofac Surg. Primary intraosseous squamous cell carcinoma in pre-existing keratocystic odontogenic tumor: A case report and literature review.
Mol Clin Oncol. Arch Iran Med. PLoS One. Recibido: 19 de octubre de Aprobado: 30 de octubre de
Cáncer de piel escamocelular
CARCINOMA ESCAMOCELULAR (cáncer de piel)